High-throughput xenoantibody discovery service.
Immune exposures to non-human proteins (“xenoantigens”), are a major component of an individual’s unique antibody fingerprint. Xenoantigens originate from plants, animals, foods, fungi, insects, the microbiome, pathogenic bacteria, parasites, and most anything else a person might encounter across their lifetime.
ANTYGEN™ XenScan™ service provides an unparalleled way to assay a patient’s xenoantigen exposure history by comprehensively analyzing xenoantibodies to a phage library displaying peptides from 604 unique xenoantigens representing 213 unique species curated by the Immune Epitope Database (IEDB) — this library contains every full-length UniProt protein with an IEDB-reported antigen that does not originate from humans, viruses, or malaria (plasmodium). This product is available as a service to both academic and industry customers.