PHAGE DISPLAY IMMUNOPRECIPITATION  SEQUENCING: PhIP-Seq

Technology Overview

PhIP-Seq in the News

PhIP-Seq: HuScan™ — Human proteome phage display

Human proteome epitope-level autoantibody profiling service via T7 phage display and immunonprecipitation sequencing. The entire UniProt human proteome — in a single assay.

Learn more about our ANTYGEN™ HuScan™ analysis services standalone or as part of a Grand Seromics assay:

HuScan: Immune Profiling Literature Citations

Mohan D et al. (2018) PhIP-Seq characterization of serum antibodies using oligonucleotide-encoded peptidomes. Nat Protoc 3:1958-1978.

Larman et al.. (2013) PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis. J Autoimmun 43:1-9.

Larman et al. (2011) Autoantigen discovery with a synthetic human peptidome. Nat Biotechnol 29:535–541.

PhIP-Seq: VirScan™ — Human virome phage display

Human virome epitope-level antiviral antibody profiling service via T7 phage display and immunonprecipitation sequencing. The entire UniProt human virome — in a single assay.

Learn more about our ANTYGEN™ VirScan™ analysis services standalone or as part of a Grand Seromics assay:

VirScan: Immune Profiling Literature Citations

Xu GJ et al. (2015) Viral immunology. Comprehensive serological profiling of human populations using a synthetic human virome. Science 348:(6239):aaa0698.

Isnard P et al. (2019) Temporal virus serological profiling of kidney graft recipients using VirScan. Proc Natl Acad Sci USA 116:10899-10904.